SCHEMBL1702573

SCHEMBL1702573

CCN(CC)c1ccc(C=NN(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.73
GAA P10253 4/20 0.73
MAPK1 P28482 3/20 0.73
HTT P42858 2/20 0.73
RAB9A P51151 3/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 12/20 0.49
KDM4E B2RXH2 7/20 0.49
POLB P06746 1/20 0.47
EIF4H Q15056 1/20 0.47
HPGD P15428 3/20 0.46
ALOX12 P18054 1/20 0.46
LMNA P02545 6/20 0.45
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
S100B P04271 1/20 0.44
SMN1; SMN2 Q16637 6/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
BLM P54132 1/20 0.42
TDP1 Q9NUW8 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702571 1.00 MAPT (0.73) MAPTGAAMAPK1HTTRAB9A
SCHEMBL9876003 0.87 MAPT (0.55) MAPTGAAMAPK1HTTRAB9A
SCHEMBL358635 0.86 MAPT (0.55) MAPTGAAMAPK1HTTRAB9A
SCHEMBL358634 0.86 MAPT (0.55) MAPTGAAMAPK1HTTRAB9A
SCHEMBL4668743 0.84 MAPT (1.00) MAPTGAAMAPK1HTTRAB9A
SCHEMBL9775471 0.84 MAPT (0.71) MAPTGAAMAPK1HTTRAB9A
SCHEMBL9775473 0.84 MAPT (0.71) MAPTGAAMAPK1HTTRAB9A
SCHEMBL4668744 0.84 MAPT (1.00) MAPTGAAMAPK1HTTRAB9A
SCHEMBL12313273 0.84 MAPT (0.53) MAPTGAAMAPK1HTTRAB9A
SCHEMBL1702562 0.84 MAPT (0.51) MAPTGAAMAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
US-5750296-A Photo-conductive composition and CRT bulb having photo-conductive layer formed of the same SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1998-05-12 US claimed
EP-0415864-B1 Electrophotographic photoconductor LEXMARK INT INC (US) 1997-06-04 EP claimed
EP-0462406-B1 An electrophotographic photosensitive material NEC CORP (JP) 1994-04-20 EP claimed
US-5130215-A Electrophotographic photoconductor contains ordered copolyester polycarbonate binder LEXMARK INTERNATIONAL, INC. (US) 1992-07-14 US claimed
EP-0415864-A1 Electrophotographic photoconductor LEXMARK INTERNATIONAL, INC. (US) 1991-03-06 EP claimed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP claimed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US claimed
US-20150185629-A1 Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-20150185627-A1 Method of Producing Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-8178265-B2 Electrophotographic photoreceptor having a spectral marker and electrophotographic printer using the same LEXMARK INTERNATIONAL, INC. (US) 2012-05-15 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-7955769-B2 Control of crazing, cracking or crystallization of a charge transport layer in a photoconductor LEXMARK INTERNATIONAL, INC. (US) 2011-06-07 US disclosed
US-20100167191-A1 Electrophotographic Photoreceptor Having a Spectral Marker and Electrophotographic Printer Using the Same BANK TRUST COMPANY, NATIONAL ASSOCIATION 2010-07-01 US disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4423129-A CHARGE TRANSFER COMPOUND CANON KABUSHIKI KAISHA (JP) 1983-12-27 US disclosed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US disclosed