SCHEMBL4668744

SCHEMBL4668744

CCN(CC)c1ccc(C=NN(c2ccccc2)c2ccccc2)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 1.00
GAA P10253 6/20 1.00
HTT P42858 3/20 1.00
MAPK1 P28482 3/20 1.00
ALDH1A1 P00352 13/20 0.69
KDM4E B2RXH2 8/20 0.69
HPGD P15428 3/20 0.64
ALOX12 P18054 1/20 0.64
LMNA P02545 6/20 0.63
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
RAB9A P51151 2/20 0.61
NPC1 O15118 1/20 0.61
TDP1 Q9NUW8 4/20 0.60
CRHBP P24387 1/20 0.60
CRHR2 Q13324 1/20 0.60
SMN1; SMN2 Q16637 5/20 0.58
L3MBTL1 Q9Y468 1/20 0.57
BLM P54132 1/20 0.56
THRB P10828 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4668743 1.00 MAPT (1.00) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL5632591 0.88 MAPT (0.78) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL5632589 0.88 MAPT (0.78) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL4668751 0.85 MAPT (0.74) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL4668750 0.85 MAPT (0.74) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL1702571 0.84 MAPT (0.73) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL1702573 0.84 MAPT (0.73) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL4669501 0.84 MAPT (0.72) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL4669503 0.84 MAPT (0.72) MAPTGAAHTTMAPK1ALDH1A1
SCHEMBL9775473 0.83 MAPT (0.71) MAPTGAAHTTMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445877-B2 Charge transport materials having a central disulfane linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-04 US disclosed
US-7427460-B2 Hydrazone-based charge transport materials having an ethylenically unsaturated group SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-09-23 US disclosed
EP-1443365-B1 Organophotoreceptor with charge transport material having an amino-substituted hydrazone group and an epoxy group SAMSUNG ELECTRONICS CO LTD (KR) 2008-02-20 EP disclosed
US-7326506-B2 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-02-05 US disclosed
EP-1418469-B1 Organophotoreceptor with charge transport compound with hydrazone groups SAMSUNG ELECTRONICS CO LTD (KR) 2007-04-04 EP disclosed
EP-1600821-B1 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO LTD (KR) 2007-02-28 EP disclosed
US-7183028-B2 Organophotoreceptor with novel charge transport compounds having an epoxy group SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-02-27 US disclosed
US-7179574-B2 Hydrazone-based charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-02-20 US disclosed
EP-1584985-B1 Hydrazone-based charge transport materials SAMSUNG ELECTRONICS CO LTD (KR) 2006-12-06 EP disclosed
US-7144665-B2 Organophotoreceptor with a charge transport material having two hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-12-05 US disclosed
US-20050221213-A1 Hydrazone-based charge transport materials S-PRINTING SOLUTION CO., LTD. (KR) 2005-10-06 US disclosed
US-20040170910-A1 Organophotoreceptor with a charge transport material having two hydrazone groups S-PRINTING SOLUTION CO., LTD. (KR) 2004-09-02 US disclosed
EP-1452924-A1 Organophotoreceptor with charge transport material having two hydrazone groups Samsung Electronics Co., Ltd. (KR) 2004-09-01 EP disclosed
US-20040157145-A1 Organophotoreceptor with novel charge transport compounds having an epoxy group S-PRINTING SOLUTION CO., LTD. (KR) 2004-08-12 US disclosed
US-20040152002-A1 Organophotoreceptor with charge transport material having two linked hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-08-05 US disclosed
EP-1443039-A1 Organophotoreceptor with charge transport material having two linked hydrazone groups Samsung Electronics Co., Ltd. (KR) 2004-08-04 EP disclosed
EP-1443365-A1 Organophotoreceptor with charge transport material having an amino-substituted hydrazone group and an epoxy group Samsung Electronics Co., Ltd. (KR) 2004-08-04 EP disclosed
US-20040106054-A1 Organophotoreceptor with charge transport compound with hydrazone groups S-PRINTING SOLUTION CO., LTD. (KR) 2004-06-03 US disclosed
EP-1418469-A2 Organophotoreceptor with charge transport compound with hydrazone groups Samsung Electronics Co., Ltd. (KR) 2004-05-12 EP disclosed
US-5925486-A Imaging members with improved wear characteristics LEXMARK INTERNATIONAL, INC. (US) 1999-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040157145-A1 Organophotoreceptor with novel charge transport compounds having an epoxy group SLC43A1, SLC16A3, SLC26A3 MAPT 4115/4885GAA 2662/4885HTT 2984/4885
US-20050221213-A1 Hydrazone-based charge transport materials SLC9A1, SLC9B2, SLC9A2 MAPT 3794/4885GAA 3662/4885HTT 240/4885
US-20040170910-A1 Organophotoreceptor with a charge transport material having two hydrazone groups SLC16A7, SLC43A1, SLC16A8 MAPT 3554/4885GAA 2543/4885HTT 1403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.