SCHEMBL9775697

SCHEMBL9775697

CC(=O)OC(CCCl)OC(C)=O.CC(=O)O[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
GALR3 O60755 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204649 0.91 TSHR (0.42) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10782810 0.77 TSHR (0.50) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL6897262 0.73 TSHR (0.42) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL2230506 0.72 TSHR (0.46) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL202086 0.71
SCHEMBL7556851 0.71
SCHEMBL29004399 0.71 THRB (0.43) TSHRGALR3MAPTBLMSMN1; SMN2
SCHEMBL190306 0.70 TSHR (0.43) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10786488 0.70 TSHR (0.43) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL18732098 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049414-A Antireflection solution for optical parts and method for antireflection treatment using said solution ITO OPTICAL INDUSTRIAL CO., LTD. (JP) 1991-09-17 US disclosed
US-4183874-A CURABLE BY HYDROLYSIS AND CROSSLINKING OF END GROUPS UNION CARBIDE CORPORATION (US) 1980-01-15 US disclosed
US-4093600-A COUPLING OR SIZING AGENTS FOR MINERAL FIBERS UNION CARBIDE CORPORATION (US) 1978-06-06 US disclosed