Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.36 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.36 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.36 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398756 | 0.86 | HPGD (0.47) | HPGDALOX15TOP2AITGB3ITGA2B | |
| SCHEMBL9399259 | 0.85 | KMT2A (0.45) | CNR2CNR1MEN1ALDH1A1MAPK1 | |
| SCHEMBL9399597 | 0.85 | ALOX15 (0.48) | HPGDALOX15TOP2AITGB3ITGA2B | |
| SCHEMBL9398985 | 0.85 | KMT2A (0.45) | CNR2CNR1MEN1ALDH1A1MAPK1 | |
| SCHEMBL9398847 | 0.85 | ALOX15 (0.48) | HPGDALOX15TOP2AITGB3ITGA2B | |
| SCHEMBL9399336 | 0.83 | MAPT (0.38) | ALOX15CNR2CNR1ITGB3ITGA2B | |
| SCHEMBL9432624 | 0.82 | HPGD (0.43) | HPGDALOX15TOP2ACNR2CNR1 | |
| SCHEMBL9399653 | 0.82 | ESR1 (0.40) | HPGDCNR2CNR1RARB | |
| SCHEMBL9398830 | 0.81 | MAPT (0.37) | ALOX15CNR2CNR1ITGB3ITGA2B | |
| SCHEMBL9399215 | 0.81 | HTR1A (0.41) | HPGDCNR2CNR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0084194-B1 | LIQUID CRYSTAL MIXTURES | MERCK PATENT GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0084194-A1 | Liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |