Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569043 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL10571237 | 0.84 | GAA (0.54) | ALDH1A1CYP2C19CYP3A4KMT2AGAA | |
| SCHEMBL31294795 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL10569206 | 0.83 | CA2 (0.46) | ALDH1A1CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL11287878 | 0.82 | GAA (0.48) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL27887649 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL27871453 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL10568155 | 0.82 | PLCG1 (0.52) | ALDH1A1CYP2C19KMT2AGAA | |
| SCHEMBL10361091 | 0.81 | TDP1 (0.56) | ALDH1A1CYP2C19MAPTSMN1; SMN2GAA | |
| SCHEMBL10571563 | 0.81 | TDP1 (0.56) | ALDH1A1CYP2C19MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996158-A | Optical resolution of racemic alcohols | LION CORPORATION, 3-7, HONJO 1-CHOME, SUMIDA-KU, TOKYO, JAPAN | 1991-02-26 | — | — | US | disclosed |