Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9775831 | 1.00 | HIF1A (0.32) | HIF1AHTR2ASNCA | |
| Bromide SCHEMBL9775834 | 0.78 | MAOB (0.32) | HIF1A | |
| Bromide SCHEMBL9775843 | 0.78 | MAOB (0.32) | HIF1A | |
| Bromide SCHEMBL8152923 | 0.71 | MEN1 (0.34) | HIF1A | |
| SCHEMBL691655 | 0.69 | TRPA1 (0.47) | HIF1AHTR2A | |
| SCHEMBL691654 | 0.69 | TRPA1 (0.47) | HIF1AHTR2A | |
| Bromide SCHEMBL30063051 | 0.69 | EPHX2 (0.33) | — | |
| Bromide SCHEMBL2452738 | 0.69 | HIF1A (0.39) | HIF1ASNCA | |
| Bromide SCHEMBL11584557 | 0.68 | HIF1A (0.44) | HIF1AHTR2ASNCA | |
| Bromide SCHEMBL16004643 | 0.68 | HIF1A (0.44) | HIF1AHTR2ASNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011683-A | 13,14,15-unsaturated hydrocarbon | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1991-04-30 | — | — | US | disclosed |
| US-5008478-A | Aids in insect control | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1991-04-16 | — | — | US | disclosed |