SCHEMBL691654

SCHEMBL691654

CC/C=C/C(C)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.47
LMNA P02545 2/20 0.45
TAAR1 Q96RJ0 4/20 0.40
ADRA2C P18825 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ADRA2A P08913 1/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 2/20 0.38
AOC3 Q16853 2/20 0.36
CHRM2 P08172 1/20 0.36
ADRA1A P35348 1/20 0.36
RGS12 O14924 1/20 0.36
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL691655 1.00 TRPA1 (0.47) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL16167117 0.83 TRPA1 (0.44) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL16167114 0.83 TRPA1 (0.44) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL16167538 0.81 TRPA1 (0.44) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL96430 0.81 LMNA (0.48) TRPA1LMNAADRA2CKDM4EADRA2A
SCHEMBL19752442 0.81 TRPA1 (0.44) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL16167537 0.81 TRPA1 (0.44) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL6014436 0.81 TAAR1 (0.48) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL6014433 0.81 TAAR1 (0.48) TRPA1LMNATAAR1ADRA2CKDM4E
SCHEMBL2170476 0.81 TRPA1 (0.53) TRPA1LMNATAAR1ADRA2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2984055-B1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA INC (US) 2018-10-17 EP disclosed
US-9758445-B2 Preparation of surfactants via cross-metathesis MATERIA, INC. (US) 2017-09-12 US disclosed
US-9663459-B2 Preparation of surfactants via cross-metathesis MATERIA, INC. (US) 2017-05-30 US disclosed
US-20160186094-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA, INC. 2016-06-30 US disclosed
US-20160145204-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA, INC. 2016-05-26 US disclosed
EP-2984055-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS Materia, Inc. (US) 2016-02-17 EP disclosed
WO-2015126462-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA, INC. (US) 2015-08-27 WO disclosed
WO-2014169080-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA, INC. (US) 2014-10-16 WO disclosed
EP-2421984-A1 COMPOSITIONS AND METHODS FOR FERMENTATION OF BIOMASS Qteros, Inc. (US) 2012-02-29 EP disclosed
WO-2010123932-A9 COMPOSITIONS AND METHODS FOR FERMENTATION OF BIOMASS QTEROS, INC. (US) 2011-06-09 WO disclosed
WO-2010123932-A1 COMPOSITIONS AND METHODS FOR FERMENTATION OF BIOMASS QTEROS, INC. (US) 2010-10-28 WO disclosed
US-7348065-B2 Slipping property imparting agent for clear coating and clear coating paper having the agent applied thereon NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2008-03-25 US disclosed
US-20050176908-A1 Slipping property imparting agent for clear coating and clear coating paper having the agent applied thereon SAN NOPCO LIMITED (JP) 2005-08-11 US disclosed
US-5786100-A COATING COMPRISES LATEX OF CONJUGATED DIENE, ETHYLENICALLY UNSATURATED ACID, AND ETHYLENICALLY UNSATURATED AROMATIC COMPOUND, ESTER, AMIDE, AMINE, OR ALKENYL CYANIDE, AND ALPHA METHYL STYRENE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-07-28 US disclosed
US-5637644-A Process for producing copolymer latex and paper coating composition, carpet backing composition or adhesive composition comprising said latex JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-06-10 US disclosed
US-5444118-A Emulsion polymerizing in two stages conjugated diene, unsaturated acid, other unsaturated compound in presence of alpha-methylstyrene dimer JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-08-22 US disclosed
EP-0407059-B1 Process for producing copolymer latex and paper coating composition, carpet backing composition or adhesive composition comprising said latex JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-11-09 EP disclosed
EP-0407059-A2 Process for producing copolymer latex and paper coating composition, carpet backing composition or adhesive composition comprising said latex JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160186094-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS SMURF2, EPHX2, SMURF1 TRPA1 1614/4885LMNA 1872/4885TAAR1 3250/4885
US-20160145204-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS SMURF2, SMURF1, ABCB4 TRPA1 426/4885LMNA 1327/4885TAAR1 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.