Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775849 | 0.68 | MAPT (0.36) | PFKFB3MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL9775837 | 0.68 | MAPT (0.36) | PFKFB3MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL949418 | 0.67 | — | — | |
| SCHEMBL3001217 | 0.67 | KDM4E (0.39) | HPGDALDH1A1CYP3A4KDM4EMEN1 | |
| SCHEMBL9657273 | 0.66 | KMT2A (0.37) | MAPTHPGDALDH1A1CYP3A4KDM4E | |
| SCHEMBL9657267 | 0.66 | KMT2A (0.37) | MAPTHPGDALDH1A1CYP3A4KDM4E | |
| SCHEMBL3010718 | 0.65 | KDM4E (0.37) | HPGDALDH1A1CYP3A4KDM4ENPC1 | |
| Fumaric Acid SCHEMBL28937804 | 0.64 | HCAR2 (0.36) | MAPTHPGDALDH1A1CYP3A4KDM4E | |
| SCHEMBL3008390 | 0.64 | KDM4E (0.41) | HPGDALDH1A1KDM4ENPC1CYP1A2 | |
| SCHEMBL1134128 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019586-A | 5-Hydroxytryptamine Receptor Antagonists | GLAXO GROUP LIMITED | 1991-05-28 | — | — | US | disclosed |