Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarinic Acid Methyl Ether SCHEMBL14889493 | 0.93 | GAA (0.50) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL303215 | 0.85 | PLA2G2D (0.42) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL126602 | 0.85 | PLA2G2D (0.42) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL20480680 | 0.82 | CYSLTR2 (0.43) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL8025820 | 0.81 | PLA2G2D (0.42) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL2226678 | 0.79 | MAPT (0.59) | ALDH1A1KDM4ESMN1; SMN2AKR1B10AKR1B1 | |
| SCHEMBL8007239 | 0.79 | MAPT (0.59) | ALDH1A1KDM4ESMN1; SMN2AKR1B10AKR1B1 | |
| SCHEMBL4421062 | 0.79 | KDM4E (0.71) | ALDH1A1KDM4EHPGDSMN1; SMN2AKR1B10 | |
| SCHEMBL8872479 | 0.79 | KDM4E (0.71) | ALDH1A1KDM4EHPGDSMN1; SMN2AKR1B10 | |
| SCHEMBL466048 | 0.79 | KDM4E (0.71) | ALDH1A1KDM4EHPGDSMN1; SMN2AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041244-A | Chromophore and polymeric liquid gel | LIQUID SUNGLASSES CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| US-4765977-A | HIGH MOLECULAR WEIGHT ETHYLENE-MALEIC ANHYDRIDE POLYMER AND OCULAR CHROMOPHORE | LIQUID SUNGLASSES CORPORATION, | 1988-08-23 | — | — | US | disclosed |