SCHEMBL466048

SCHEMBL466048

CCCCCCCCOC(=O)/C=C/c1ccccc1OC

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.71
ALDH1A1 P00352 4/20 0.71
HPGD P15428 3/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
NFE2L2 Q16236 2/20 0.58
TFEB P19484 1/20 0.57
AKR1B10 O60218 5/20 0.56
AKR1B1 P15121 5/20 0.56
KMT2A Q03164 2/20 0.55
MAPT P10636 2/20 0.55
APP P05067 4/20 0.54
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.52
LMNA P02545 1/20 0.52
BCHE P06276 1/20 0.52
RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4629237 1.00 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL4421062 1.00 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL8872224 1.00 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL8872479 1.00 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
Hydrochloric Acid SCHEMBL10437236 0.99 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL5177689 0.99 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL1614877 0.96 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL19244312 0.96 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL19244433 0.90 KDM4E (0.72) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL2474892 0.90 KDM4E (0.72) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866033-B1 SUNSCREEN AEROSOL SPRAY ENSIGN LABORATORIES PTY LTD (AU) 2017-04-19 EP claimed
US-20150272844-A1 Topical skin care formulations HOLYFIELD LOUISE (US) 2015-10-01 US claimed
US-9060946-B2 Topical skin care formulations HOLYFIELD LOUISE (US) 2015-06-23 US claimed
US-20150132392-A1 INORGANIC COMPOSITE POWDER COATED WITH OCTYL METHOXYCINNAMATE, AND ULTRAVIOLET BLOCKING COSMETIC COMPOSITION USING SAME CHEMLAND. CO., LTD (KR) 2015-05-14 US claimed
US-20150064125-A1 Topical skin care formulations HOLYFIELD LOUISE (US) 2015-03-05 US claimed
US-20140322149-A1 COMPOUND USEFUL FOR TREATING CELLULITE SIGMA TAU IND FARMACEUTI (IT) 2014-10-30 US claimed
US-8192506-B2 Compositions for dyeing keratin-containing fibers KELLY VAN GOGH, INC. (US) 2012-06-05 US claimed
US-20110217252-A1 COMPOUND USEFUL FOR TREATING CELLULITE SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2011-09-08 US claimed
EP-2344153-A1 COMPOUND USEFUL FOR TREATING CELLULITE SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) 2011-07-20 EP claimed
WO-2010054978-A1 COMPOUND USEFUL FOR TREATING CELLULITE SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2010-05-20 WO claimed
US-20090061001-A1 SUNSCREEN AEROSOL SPRAY ENSIGN LABORATORIES PTY LTD (AU) 2009-03-05 US claimed
WO-2008138393-A1 GEL USEFUL FOR THE DELIVERY OF COSMETIC ACTIVE INGREDIENTS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2008-11-20 WO claimed
US-20080279900-A1 GEL USEFUL FOR THE DELIVERY OF COSMETIC ACTIVE INGREDIENTS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA (IT) 2008-11-13 US claimed
EP-1866033-A1 SUNSCREEN AEROSOL SPRAY Ensign Laboratories PTY LTD (AU) 2007-12-19 EP claimed
WO-2006099687-A1 SUNSCREEN AEROSOL SPRAY ENSIGN LABORATORIES PTY LTD (AU) 2006-09-28 WO claimed
US-20040014700-A1 Novel oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents LVMH RECHERCHE (FR) 2004-01-22 US claimed
EP-0613368-B1 SKIN REGENERATING COSMETIC COMPOSITION CAOLA COSMETICS AND MIXED HOUS (HU) 1997-10-08 EP claimed
US-5478561-A Emulsifying water in mixture of mineral oils and other oils with nonionic polymeric lipophilic emulsifier, then adding more water which contains a hydrophilic emulsifier and stirring without shear until phase inversion occurs LANCASTER GROUP AG (DE) 1995-12-26 US claimed
US-4765977-A HIGH MOLECULAR WEIGHT ETHYLENE-MALEIC ANHYDRIDE POLYMER AND OCULAR CHROMOPHORE LIQUID SUNGLASSES CORPORATION, 1988-08-23 US claimed
EP-0085334-A2 Substantive topical compositions PLOUGH, INC. (a Delaware corporation) (US) 1983-08-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080279900-A1 GEL USEFUL FOR THE DELIVERY OF COSMETIC ACTIVE INGREDIENTS SLC25A20, CRAT, CUTA KDM4E 2357/4885ALDH1A1 2427/4885HPGD 1370/4885
US-20150132392-A1 INORGANIC COMPOSITE POWDER COATED WITH OCTYL METHOXYCINNAMATE, AND ULTRAVIOLET BLOCKING COSMETIC COMPOSITION USING SAME OSTC, ERCC4, MCCC2 KDM4E 418/4885ALDH1A1 3150/4885HPGD 3411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.