Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | TFEB | P19484 | 1/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629237 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL466048 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL8872224 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL8872479 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| Hydrochloric Acid SCHEMBL10437236 | 0.99 | KDM4E (0.73) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL5177689 | 0.99 | KDM4E (0.73) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL1614877 | 0.96 | KDM4E (0.73) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL19244312 | 0.96 | KDM4E (0.73) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL19244433 | 0.90 | KDM4E (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL2474892 | 0.90 | KDM4E (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370657-B2 | Treatment of Collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene | CURNA, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20170073680-A1 | TREATMENT OF COLLAGEN GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A COLLAGEN GENE | CURNA, INC. | 2017-03-16 | — | — | US | disclosed |
| EP-1187598-B1 | MICROPIGMENT MIXTURE | BASF SE (DE) | 2009-10-21 | — | — | EP | disclosed |