Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 10/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682682 | 0.85 | TTR (0.50) | TTRALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL9178147 | 0.84 | TTR (0.58) | TTRALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL9649533 | 0.84 | CASP6 (0.37) | TTRALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL6938223 | 0.81 | SUMO2 (0.39) | TTRALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL31463177 | 0.80 | TTR (0.66) | TTRALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL5675047 | 0.80 | TTR (0.66) | TTRALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL9177053 | 0.78 | TTR (0.46) | TTRSENP3SENP2SENP1SUMO2 | |
| SCHEMBL9776655 | 0.78 | SENP3 (0.41) | TTRALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL9776593 | 0.78 | TTR (0.41) | TTRALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL9808418 | 0.77 | APEX1 (0.44) | TTRALDH1A1HSD17B10SENP2SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003053-A | Water-soluble monoazo compounds containing a p-aminophenylamino- and chloro- or fluoro-substituted triazinylamino group and a fiber-reactive group selected from the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
| US-4902786-A | Phenylazonaphthol or naphthylazonaphthol compounds containing a fibre-reactive aminophenylamino-substituted halogen-s-triazinylamino group and a fibre-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-20 | — | — | US | disclosed |
| US-4775746-A | Water-soluble monoazo compounds containing a fiber-reactive group of the vinylsulfone series and having a sulfonaphthol coupling component with a phenylaminotriazinylamino substituent, suitable as dyestuffs | HOECHST AKTIENGESELLSHAFT (DE) | 1988-10-04 | — | — | US | disclosed |
| US-4757136-A | Water-soluble Azo compounds containing fiber-reactive groups and having a sulfo-naphthol coupling component with a triazinylamino substituent suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| US-4740592-A | Water-soluble azo compounds containing fiber-reactive groups and having a sulfo-naphthal coupling component with a triazinylamino substituent suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| US-4731441-A | Water-soluble azo compounds containing, as fiber-reactive groups, a (nitrophenylamino-phenylamino)-chloro-triazinylamino group and groups of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |
| US-4703111-A | Water-soluble compounds containing one or two (nitrophenylamino)-phenylamino-chlorotriazinylamino groups, the nitrophenylamino being additionally substituted by a fiber-reactive group of the vinylsulfonyl series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT A CORP. OF GERMANY (DE) | 1987-10-27 | — | — | US | disclosed |
| US-4701523-A | Water-soluble disazo compounds containing one or two (nitro-phenylamino)-phenylamino-chlorotriazinylamino groups, the nitro-phenylamino being additionally substituted by a fiber-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-20 | — | — | US | disclosed |
| US-4659807-A | Water-soluble pyridone monoazo compounds suitable as fiber reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |