SCHEMBL9776643

SCHEMBL9776643

O=S(=O)(O)c1ccccc1C(O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.41
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TTR P02766 2/20 0.39
HSD11B1 P28845 4/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
FABP4 P15090 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
MAPK14 Q16539 1/20 0.36
NR4A1 P22736 1/20 0.35
PGAM1 P18669 1/20 0.34
CYP1A2 P05177 1/20 0.34
ALDH1A1 P00352 4/20 0.33
TDP1 Q9NUW8 2/20 0.33
GAA P10253 2/20 0.33
CHAT P28329 1/20 0.33
SNCA P37840 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3136914 0.82 MYC (0.41) MYCTSHRSMN1; SMN2TTRHSD11B1
SCHEMBL664385 0.82 TSHR (0.48) MYCTSHRSMN1; SMN2TTRHSD11B1
SCHEMBL29161539 0.81 TSHR (0.41) MYCTSHRSMN1; SMN2TTRHSD11B1
Hydrochloric Acid SCHEMBL27290976 0.80 TSHR (0.46) MYCTSHRSMN1; SMN2TTRHSD11B1
SCHEMBL247640 0.80 KMT2A (0.56) HSD11B1MEN1KMT2AALDH1A1TDP1
SCHEMBL3135389 0.80 MYC (0.40) MYCTSHRSMN1; SMN2TTRHSD11B1
SCHEMBL29624178 0.80 KMT2A (0.56) HSD11B1MEN1KMT2AALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL27814408 0.80 TSHR (0.46) MYCTSHRSMN1; SMN2TTRHSD11B1
SCHEMBL646231 0.80 MYC (0.40) MYCTSHRSMN1; SMN2TTRHSD11B1
SCHEMBL8936569 0.80 MYC (0.44) MYCTSHRSMN1; SMN2TTRHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5009925-A Aromatic sulfonic acid derivative dispersing agent AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed