Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 11/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977697 | 1.00 | ALOX5AP (0.51) | ALOX5APCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL977695 | 1.00 | ALOX5AP (0.51) | ALOX5APCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL977688 | 1.00 | ALOX5AP (0.51) | ALOX5APCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL977086 | 0.86 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL977088 | 0.86 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL976621 | 0.84 | ALOX5AP (0.57) | ALOX5AP | |
| SCHEMBL976620 | 0.84 | ALOX5AP (0.57) | ALOX5AP | |
| SCHEMBL977784 | 0.84 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL977786 | 0.84 | ALOX5AP (0.58) | ALOX5AP | |
| SCHEMBL12920642 | 0.84 | ALOX5AP (0.53) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | PTGIS, PTGS1, LTC4S | ALOX5AP 47/4885CHRNA7 4004/4885HTR3A 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.