Phosphoric Acid

Phosphoric Acid

SCHEMBL9778089

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nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADRB3 known ✓ P13945 1/20 0.30
CA2 P00918 1/20 0.46
SLC34A1 Q06495 1/20 0.42
FDPS P14324 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MMP2 P08253 1/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TYMS P04818 1/20 0.33
LMNA P02545 2/20 0.31
PDE4D Q08499 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL1853121 1.00
Phosphoric Acid SCHEMBL27167629 1.00 CA2 (0.46) CA2SLC34A1FDPSKDM4EMMP2
Phosphoric Acid SCHEMBL17937930 0.94 CA2 (0.42) CA2SLC34A1FDPSKDM4EMMP2
Phosphoric Acid SCHEMBL28130319 0.94 CA2 (0.42) CA2SLC34A1FDPSKDM4EMMP2
Phosphoric Acid SCHEMBL28130320 0.94
Phosphoric Acid SCHEMBL28092183 0.94
Phosphoric Acid SCHEMBL8934854 0.94 CA2 (0.50) CA2SLC34A1FDPSKDM4EMMP2
Phosphoric Acid SCHEMBL162699 0.94
Phosphoric Acid SCHEMBL31567892 0.94 CA2 (0.50) CA2SLC34A1FDPSKDM4EMMP2
Phosphoric Acid SCHEMBL8744243 0.94 CA2 (0.50) CA2SLC34A1FDPSKDM4EMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113638026-B Magnesium alloy surface MAO-LDH biological composite membrane layer and preparation method and application thereof 江苏科技大学 2022-06-10 CN disclosed
CN-113638026-A Magnesium alloy surface MAO-LDH biological composite membrane layer and preparation method and application thereof 江苏科技大学 2021-11-12 CN disclosed
CN-107201541-B Calcium lactate-added micro-arc oxidation electrolyte system 山东大学 2021-07-23 CN disclosed
CN-111377421-A α method for preparing gypsum and method for preparing phosphoric acid and α gypsum by using phosphorite 四川大学 2020-07-07 CN disclosed
CN-107899083-B Preparation method of super-wear-resistant high-toughness bioactive artificial hip joint 南宁越洋科技有限公司 2020-05-26 CN disclosed
CN-107961398-B Preparation method of bone tissue engineering scaffold material artificial tooth root capable of enhancing osseointegration 南宁越洋科技有限公司 2020-05-26 CN disclosed
CN-105233847-A Honeycomb ceramic catalyst, preparation method therefor and application thereof Guangdong midea refrigeration equipment co ltd 2016-01-13 CN disclosed
US-4997446-A Method and apparatus for osseous contour reconstruction INTERMEDICS ORTHOPEDICS, INC. (US) 1991-03-05 US disclosed