SCHEMBL9778154

SCHEMBL9778154

C=CCNc1ccc(C2(c3ccc(NCC=C)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
POLB P06746 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47
OPRK1 P41145 1/20 0.47
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 2/20 0.39
MITF O75030 1/20 0.39
NSD2 O96028 1/20 0.39
CASP3 P42574 1/20 0.39
HTT P42858 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052319 0.78 LMNA (0.52) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL9778153 0.77 KMT2A (0.41) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL7051594 0.75 MAPT (0.49) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL12650067 0.75 KDM4E (0.49) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL99646 0.74 CA12 (0.65) KMT2AMEN1SMN1; SMN2LMNAKDM4E
SCHEMBL8185440 0.73 LMNA (0.46) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL7048388 0.73 LMNA (0.46) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL29579333 0.73 LMNA (0.46) KMT2AMEN1POLBSMN1; SMN2LMNA
SCHEMBL20941276 0.73 IDO1 (0.32) KMT2AMEN1POLBLMNAKDM4E
Allylamine SCHEMBL9778155 0.73 LMNA (0.53) KMT2AMEN1POLBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034279-A Electrophoretically depositable coating composition of a curable resin, a reaction betueen an epoxy and a crosslinking agent MINNESOTA MINING & MANUFACTURING COMPANY (US) 1991-07-23 US claimed
US-4913968-A IONIC OR NONIONIC CURED POLYEPOXIDES; BULKY-STRUCTURED CROSSLINKER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-03 US claimed
EP-0260010-A2 Water-compatible coating resin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-16 EP claimed
EP-0260009-A2 Water-compatible coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-16 EP claimed