SCHEMBL9778262

SCHEMBL9778262

CC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11550180 0.92 MAOA (0.55) MAOA
SCHEMBL11547807 0.86 MAOA (0.57) MAOA
SCHEMBL11549880 0.85 MAOA (0.60) MAOA
SCHEMBL11552722 0.82 MAOA (0.47) MAOA
SCHEMBL11828841 0.81 MAOA (0.52) MAOA
SCHEMBL11824802 0.80 MAOA (0.51) MAOA
SCHEMBL3035516 0.77 MAOA (0.58) MAOA
SCHEMBL18020372 0.77 MAOA (0.57) MAOA
SCHEMBL11548062 0.76 CHEK1 (0.50) MAOA
SCHEMBL21666868 0.76 MAOA (0.55) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5036067-A Enzyme inhibotors MERCK & CO., INC. (US) 1991-07-30 US disclosed
US-3981887-A Sulfoxides and sulfones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-09-21 US disclosed