Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778262 | 0.85 | MAOA (0.68) | MAOA | |
| SCHEMBL11547807 | 0.83 | MAOA (0.57) | MAOAALOX5 | |
| SCHEMBL18288011 | 0.81 | ALOX5 (0.68) | ALOX5TRPA1 | |
| SCHEMBL11828841 | 0.78 | MAOA (0.52) | MAOA | |
| SCHEMBL11824802 | 0.77 | MAOA (0.51) | MAOA | |
| SCHEMBL11820319 | 0.77 | MAOA (0.48) | MAOA | |
| SCHEMBL11550180 | 0.76 | MAOA (0.55) | MAOA | |
| SCHEMBL70117 | 0.76 | ALOX5 (0.59) | ALOX5TRPA1 | |
| SCHEMBL70481 | 0.76 | ALOX5 (0.59) | ALOX5TRPA1 | |
| SCHEMBL69714 | 0.76 | CA1 (0.55) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177257-A | ANTIANAPHYLACTIC AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4145350-A | ANTIALLERGENS, TETRAZOLYL- SUBSTITUTED | BURROUGHS WELLCOME CO. (US) | 1979-03-20 | — | — | US | disclosed |