Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778270 | 0.86 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9778210 | 0.85 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9778237 | 0.83 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL11819657 | 0.78 | PTGS2 (0.48) | — | |
| SCHEMBL9778393 | 0.77 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9778277 | 0.75 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9473244 | 0.75 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL11825872 | 0.74 | PSEN1 (0.39) | — | |
| SCHEMBL9778254 | 0.74 | AHR (0.37) | — | |
| SCHEMBL11817005 | 0.73 | PSEN1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036067-A | Enzyme inhibotors | MERCK & CO., INC. (US) | 1991-07-30 | — | — | US | claimed |
| US-5036067-A | Enzyme inhibotors | MERCK & CO., INC. (US) | 1991-07-30 | — | — | US | disclosed |