Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778457 | 0.74 | LMNA (0.47) | CYP2C19CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL23177821 | 0.66 | KMT2A (0.48) | CYP1A2ALDH1A1 | |
| SCHEMBL14309737 | 0.63 | — | — | |
| SCHEMBL19492662 | 0.63 | — | — | |
| SCHEMBL6447254 | 0.62 | CYP2C19 (0.61) | CYP2A6CYP2C19CYP2E1CYP2B6CYP1A2 | |
| SCHEMBL10692201 | 0.62 | PLAU (0.39) | CYP2A6CYP2C19CYP2E1CYP2B6CYP1A2 | |
| SCHEMBL9794433 | 0.62 | — | — | |
| SCHEMBL10692195 | 0.61 | CYP2C19 (0.38) | CYP2A6CYP2C19CYP2E1CYP2B6CYP1A2 | |
| SCHEMBL16186484 | 0.61 | — | — | |
| SCHEMBL17833437 | 0.61 | CYP2E1 (0.31) | CYP2A6CYP2C19CYP2E1CYP2B6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025099-A | Cholinergic agents, cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| US-5025099-A | Cholinergic agents, cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-06-18 | — | — | US | disclosed |