Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669509 | 0.79 | L3MBTL1 (0.47) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL9778659 | 0.79 | L3MBTL1 (0.47) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL9778589 | 0.79 | TSHR (0.44) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL7307049 | 0.79 | ALDH1A1 (0.44) | TSHRKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9778646 | 0.75 | MEN1 (0.51) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL11611417 | 0.73 | CYP3A4 (0.47) | TSHRKDM4ELMNACYP3A4MAPT | |
| SCHEMBL30669513 | 0.70 | TSHR (0.67) | TSHRALDH1A1 | |
| SCHEMBL16597308 | 0.69 | TSHR (0.38) | TSHRCA1CA2CA12CA14 | |
| SCHEMBL27988010 | 0.69 | KDM4E (0.34) | TSHRABCB1CA1CA2CA12 | |
| SCHEMBL4785764 | 0.69 | TSHR (0.49) | TSHRKDM4EHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063197-A | Aromatic compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-11-05 | — | — | US | disclosed |