SCHEMBL9778779

SCHEMBL9778779

CC1(c2ccc(OCc3ccc(Cl)cc3)cc2)OCCO1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.52
MAOA P21397 5/20 0.52
APP P05067 1/20 0.51
NR4A2 P43354 1/20 0.47
FOXM1 Q08050 1/20 0.44
DHFR P00374 1/20 0.43
FFAR1 O14842 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9778561 0.94 MAOB (0.50) MAOBMAOAAPPNR4A2FOXM1
SCHEMBL9778811 0.87 MAOB (0.51) MAOBMAOAFFAR1NPC1RAB9A
SCHEMBL9778704 0.81 HRH3 (0.49) MAOBMAOAFFAR1NPC1RAB9A
SCHEMBL9778845 0.81 APP (0.51) MAOBAPPFFAR1NPC1RAB9A
SCHEMBL2084415 0.80 LMNA (0.54) MAOBMAOA
SCHEMBL9778527 0.79 MMP2 (0.51) MAOBMAOAFOXM1RAB9AHRH3
SCHEMBL10991891 0.77 MAOB (0.80) MAOBMAOAAPPNR4A2DHFR
SCHEMBL9778904 0.77 MAOB (0.51) MAOBMAOAAPPNR4A2DHFR
SCHEMBL9672654 0.74 AGXT (0.47)
SCHEMBL9778661 0.74 MAOB (0.49) MAOBMAOAAPPNR4A2FOXM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5063197-A Aromatic compound MITSUBISHI PAPER MILLS LIMITED (JP) 1991-11-05 US disclosed