Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313036 | 0.84 | CYP1A2 (0.50) | KDM4EMAPTALDH1A1GAATDP1 | |
| SCHEMBL22761948 | 0.83 | GPR55 (0.55) | KDM4EMAPTALDH1A1GAATDP1 | |
| SCHEMBL2963854 | 0.81 | CYP1A2 (0.60) | KDM4EMAPTALDH1A1GLAHPGD | |
| SCHEMBL9609733 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TDP1HPGDTSHRHSD17B10 | |
| SCHEMBL16807708 | 0.79 | AHR (0.50) | KDM4EMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL31315608 | 0.78 | CYP1A2 (0.46) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL30960395 | 0.78 | CYP2A6 (0.45) | KDM4EMAPTTDP1L3MBTL1GLA | |
| SCHEMBL30057707 | 0.78 | CYP2A6 (0.45) | KDM4EMAPTTDP1L3MBTL1GLA | |
| SCHEMBL9108240 | 0.78 | CYP2A6 (0.45) | KDM4EMAPTTDP1L3MBTL1GLA | |
| SCHEMBL20209355 | 0.77 | AHR (0.49) | KDM4EMAPTALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999369-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4910218-A | With a hydroxy containing secondary amine group | BURROUGHS WELLCOME CO. (US) | 1990-03-20 | — | — | US | disclosed |