Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 7/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | SDHB | P21912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779035 | 0.92 | PTGES2 (0.42) | HTTTDP1L3MBTL1PTGES2PGR | |
| SCHEMBL9779047 | 0.88 | HTT (0.54) | HTTTDP1L3MBTL1PTGES2PGR | |
| SCHEMBL9779001 | 0.88 | PTGES2 (0.54) | HTTTDP1L3MBTL1PTGES2PGR | |
| SCHEMBL9778890 | 0.84 | HTT (0.47) | HTTTDP1L3MBTL1NR3C1SMN1; SMN2 | |
| SCHEMBL9778880 | 0.80 | PGR (0.59) | HTTTDP1L3MBTL1PGRNR3C1 | |
| SCHEMBL9778961 | 0.80 | PTGES2 (0.52) | HTTTDP1L3MBTL1PTGES2ABCC9 | |
| SCHEMBL9778844 | 0.79 | SOS1 (0.53) | HTTTDP1L3MBTL1PGRNR3C1 | |
| SCHEMBL9779108 | 0.78 | HTT (0.56) | HTTTDP1L3MBTL1PGRSMN1; SMN2 | |
| SCHEMBL3672508 | 0.78 | HTT (0.52) | HTTTDP1L3MBTL1PTGES2PGR | |
| SCHEMBL3677240 | 0.78 | HTT (0.52) | HTTTDP1L3MBTL1PTGES2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066409-A | Novel aryl ether sulfones | THE DOW CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |