Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779368 | 0.93 | HPGD (0.54) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779547 | 0.91 | HPGD (0.53) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779270 | 0.91 | HTT (0.54) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779424 | 0.91 | HPGD (0.52) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779400 | 0.90 | TSHR (0.54) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9779490 | 0.89 | PDE2A (0.55) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779512 | 0.89 | TDP1 (0.54) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779272 | 0.89 | RXFP1 (0.52) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779369 | 0.89 | ALDH1A1 (0.51) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9779377 | 0.89 | LMNA (0.58) | HPGDKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |