Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502413 | 0.83 | ALOX5 (0.45) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| SCHEMBL202116 | 0.81 | ALOX5 (0.46) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| SCHEMBL6649268 | 0.81 | SLC1A3 (0.42) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11903029 | 0.80 | ALOX5 (0.45) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3625170 | 0.80 | ALOX5 (0.45) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| SCHEMBL6647754 | 0.80 | ALOX5 (0.38) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| SCHEMBL6753886 | 0.80 | ALOX5 (0.38) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| SCHEMBL11522091 | 0.79 | LMNA (0.40) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| SCHEMBL11248301 | 0.79 | LMNA (0.40) | ALOX5KEAP1CES2CES1ALDH1A1 | |
| SCHEMBL6032863 | 0.79 | ALOX5 (0.44) | ALOX5KEAP1CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |