Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110466 | 0.83 | CYP3A4 (0.50) | MCL1ALDH1A1HNF4ACSNK2A1CYP3A4 | |
| SCHEMBL29987613 | 0.83 | CYP3A4 (0.50) | MCL1ALDH1A1HNF4ACSNK2A1CYP3A4 | |
| SCHEMBL7773029 | 0.82 | CYP3A4 (0.49) | MCL1ALDH1A1HNF4ACSNK2A1CYP3A4 | |
| SCHEMBL7773033 | 0.82 | CYP3A4 (0.49) | MCL1ALDH1A1HNF4ACSNK2A1CYP3A4 | |
| SCHEMBL9774624 | 0.76 | MCL1 (0.67) | MCL1ALDH1A1TSHRHNF4AACMSD | |
| SCHEMBL13755067 | 0.75 | CYP3A4 (0.50) | CYP3A4CYP2D6HIF1AMEN1KMT2A | |
| SCHEMBL9774603 | 0.73 | MCL1 (0.44) | MCL1ALDH1A1TSHRHNF4ACSNK2A1 | |
| SCHEMBL317178 | 0.72 | SHBG (0.50) | ALDH1A1TSHRHNF4ACYP3A4CYP2D6 | |
| SCHEMBL11361995 | 0.72 | HNF4A (0.44) | MCL1ALDH1A1HNF4ACSNK2A1CYP3A4 | |
| SCHEMBL9652299 | 0.72 | HNF4A (0.54) | MCL1ALDH1A1HNF4ACSNK2A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034370-A | Reaction product of a salicylic acid derivative with formaldehyde and an aromatic compound | SUMITOMO DUREZ COMPANY, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |