SCHEMBL9779587

SCHEMBL9779587

C=CCOC(C)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.36
CASP1 P29466 3/20 0.33
TSHR P16473 2/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
CACNA2D1 P54289 2/20 0.31
CACNB3 P54284 1/20 0.31
CACNA1C Q13936 1/20 0.31
PGR P06401 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
CACNA2D2 Q9NY47 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PGD P52209 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8863131 0.81 PGD (0.35) TDP1SLC22A6CACNA2D1CACNB3CACNA1C
SCHEMBL29023001 0.77 TDP1 (0.45) TDP1CASP1ALDH1A1SMN1; SMN2
SCHEMBL32668791 0.77 TDP1 (0.39) TDP1TSHRALDH1A1SMN1; SMN2
SCHEMBL32668683 0.77 TDP1 (0.39) TDP1TSHRALDH1A1SMN1; SMN2
SCHEMBL9779448 0.76 MEN1 (0.36) TDP1CASP1TSHRMEN1KMT2A
SCHEMBL9507515 0.76 GABRR1 (0.42) TDP1TSHR
SCHEMBL7708142 0.75 TDP1 (0.36) TDP1CASP1SLC22A6SMN1; SMN2
SCHEMBL18959713 0.75 TDP1 (0.37) TDP1TSHRMEN1KMT2A
SCHEMBL874985 0.75 TDP1 (0.37) TDP1TSHRMEN1KMT2A
SCHEMBL170785 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5072021-A Liquid crystals MITSUI TOATSU CHEMICALS, INC. (JP) 1991-12-10 US disclosed