Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SORD | Q00796 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29534409 | 1.00 | HSP90AA1 (0.37) | HSP90AA1LMNAL3MBTL1P4HTMKDM4E | |
| Pyridine SCHEMBL27348524 | 0.92 | NAPRT (0.36) | HSP90AA1LMNAL3MBTL1P4HTMKDM4E | |
| SCHEMBL12470705 | 0.77 | LOXL2 (0.47) | LMNAALDH1A1CYP1A2CYP3A4CYP2A6 | |
| SCHEMBL29606764 | 0.71 | KDM4E (0.64) | LMNAKDM4EALDH1A1 | |
| SCHEMBL904382 | 0.71 | KDM4E (0.64) | LMNAKDM4EALDH1A1 | |
| SCHEMBL27990226 | 0.70 | CA12 (0.48) | LMNAL3MBTL1P4HTMKDM4EALDH1A1 | |
| SCHEMBL5000576 | 0.70 | HSP90AA1 (0.40) | HSP90AA1LMNAL3MBTL1P4HTMKDM4E | |
| SCHEMBL1916511 | 0.69 | KDM4E (0.33) | HSP90AA1LMNAL3MBTL1P4HTMKDM4E | |
| SCHEMBL22199088 | 0.69 | CYP2E1 (0.54) | LMNAL3MBTL1KDM4ECYP17A1CYP1A2 | |
| SCHEMBL1437298 | 0.68 | PLD1 (0.50) | LMNAP4HTMKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201929-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 广东弘烨医药科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| WO-2023151697-A1 | METTL3 INHIBITOR AND COMPOSITION, AND APPLICATION OF SAME IN MEDICINE | 四川海思科制药有限公司 | 2023-08-17 | — | — | WO | claimed |
| CN-114478523-B | Organic luminescent material and preparation method and application thereof | 西安凯翔光电科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-RE49361-E1 | Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2023-01-10 | — | — | US | claimed |
| CN-114478523-A | Organic luminescent material and preparation method and application thereof | 西安凯翔光电科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| US-10183939-B2 | Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers | REDX PHARMA PLC (GB) | 2019-01-22 | — | — | US | claimed |
| EP-3191477-B1 | FUSED BICYCLIC (HETERO)AROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF CANCERS | REDX PHARMA PLC (GB) | 2018-07-18 | — | — | EP | claimed |
| US-20170298061-A1 | FUSED BICYCLIC (HETERO)AROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF CANCERS | U.S. BANK NATIONAL ASSOCIATION | 2017-10-19 | — | — | US | claimed |
| EP-3191477-A1 | FUSED BICYCLIC (HETERO)AROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF CANCERS | Redx Pharma Plc (GB) | 2017-07-19 | — | — | EP | claimed |
| WO-2016038389-A1 | FUSED BICYCLIC (HETERO)AROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF CANCERS | REDX PHARMA PLC (GB) | 2016-03-17 | — | — | WO | claimed |
| US-20070093467-A1 | Piperidine derivatives and methods of use | CHEMOCENTRYX, INC. (US) | 2007-04-26 | — | — | US | claimed |
| US-20070088036-A1 | Piperidine derivatives and methods of use | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | US | claimed |
| WO-2007044804-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | WO | claimed |
| WO-2007044885-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | WO | claimed |
| WO-2007027734-A2 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX, INC. (US) | 2007-03-08 | — | — | WO | claimed |
| US-7090929-B2 | Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-08-15 | — | — | US | claimed |
| US-20060074121-A1 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2006-04-06 | — | — | US | claimed |
| EP-1554361-A1 | METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2005-07-20 | — | — | EP | claimed |
| US-20040072018-A1 | Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions | LG CHEM, LTD. (KR) | 2004-04-15 | — | — | US | claimed |
| WO-2004015025-A1 | METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298061-A1 | FUSED BICYCLIC (HETERO)AROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF CANCERS | BRAF, ARAF, RAF1 | HSP90AA1 1895/4885LMNA 2490/4885L3MBTL1 786/4885 |
| US-20060074121-A1 | Bicyclic and bridged nitrogen heterocycles | CCR3, CCR1, CCR2 | HSP90AA1 1950/4885LMNA 3658/4885L3MBTL1 2338/4885 |
| US-20070093467-A1 | Piperidine derivatives and methods of use | CCR1, CCR3, CCR4 | HSP90AA1 1201/4885LMNA 3293/4885L3MBTL1 1934/4885 |
| US-20070088036-A1 | Piperidine derivatives and methods of use | CCR1, CCR3, CCR4 | HSP90AA1 1201/4885LMNA 3293/4885L3MBTL1 1934/4885 |
| US-10183939-B2 | Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers | BRAF, ARAF, RAF1 | HSP90AA1 1895/4885LMNA 2490/4885L3MBTL1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.