SCHEMBL9779776

SCHEMBL9779776

Cc1cnc(C(O)=S)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
PLAU P00749 3/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
MAPT P10636 1/20 0.31
GLA P06280 1/20 0.31
HPGD P15428 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
SSTR4 P31391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9779721 0.98 ALDH1A1 (0.39) ALDH1A1PLAUCCR1CCR5CCR8
SCHEMBL1105993 0.80 MEN1 (0.43) ALDH1A1MAPTGLAHPGDTRPM8
SCHEMBL18784152 0.79 PLAU (0.46) ALDH1A1PLAUMAPTGLAHPGD
SCHEMBL9786016 0.77 ALDH1A1 (0.35) ALDH1A1MAPTHPGDSSTR4
SCHEMBL10002413 0.74 PARP1 (0.42) ALDH1A1PLAUNOS3NOS1NOS2
SCHEMBL24661703 0.72 ATM (0.47) ALDH1A1MAPTKDM4E
SCHEMBL22363326 0.71 GAA (0.41) ALDH1A1MAPTHPGDKDM4E
SCHEMBL4570475 0.70
SCHEMBL17173720 0.69 MAPT (0.51) ALDH1A1MAPTKDM4E
SCHEMBL153364 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4995902-A Novel herbicides CIBA-GEIGY CORPORATION (US) 1991-02-26 US disclosed