Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21905409 | 0.80 | PLAU (0.42) | PLAUALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL9779776 | 0.79 | ALDH1A1 (0.40) | PLAUALDH1A1HPGDMAPTGLA | |
| SCHEMBL287761 | 0.78 | LMNA (0.47) | PLAUALDH1A1LMNAL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL9779721 | 0.78 | ALDH1A1 (0.39) | PLAUALDH1A1HPGDMAPTGLA | |
| SCHEMBL23413510 | 0.77 | LMNA (0.46) | PLAUALDH1A1LMNAL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL20139726 | 0.77 | LMNA (0.46) | PLAUALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL28002539 | 0.76 | L3MBTL1 (0.44) | PLAUALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL3580724 | 0.74 | L3MBTL1 (0.43) | PLAUALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL7692886 | 0.72 | LMNA (0.42) | PLAUALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL30143410 | 0.72 | PLAU (0.48) | PLAUALDH1A1LMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162795-A1 | METHOD FOR MANUFACTURING 3-(ALKYL SULFONYL)PYRIDINE-2-CARBOXYLIC ACID | Sumitomo Chemical Company, Limited (JP) | 2017-05-03 | — | — | EP | disclosed |