SCHEMBL977997

SCHEMBL977997

O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.63
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 1/20 0.52
AKT1 P31749 2/20 0.50
NFE2L2 Q16236 1/20 0.48
RECQL P46063 3/20 0.45
MAPT P10636 3/20 0.45
PLIN1 O60240 2/20 0.45
LMNA P02545 2/20 0.45
PLIN5 Q00G26 2/20 0.45
ABHD5 Q8WTS1 2/20 0.45
BCHE P06276 1/20 0.45
TNFRSF1A P19438 1/20 0.45
ACHE P22303 1/20 0.45
MAOB P27338 1/20 0.45
CYP1B1 Q16678 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
HDAC1 Q13547 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19033787 1.00 HSP90AA1 (0.63) HSP90AA1ALDH1A1TDP1MAPK1AKT1
SCHEMBL20677772 0.90 HSP90AA1 (0.58) HSP90AA1ALDH1A1TDP1MAPK1AKT1
SCHEMBL20677796 0.88 HSP90AA1 (0.56) HSP90AA1ALDH1A1MAPK1MAPTLMNA
SCHEMBL3694184 0.87 HSP90AA1 (0.54) HSP90AA1ALDH1A1TDP1MAPTLMNA
SCHEMBL3923560 0.87 HSP90AA1 (0.54) HSP90AA1ALDH1A1TDP1MAPTLMNA
SCHEMBL9539946 0.87 HSP90AA1 (0.54) HSP90AA1ALDH1A1MAPK1MAPTLMNA
SCHEMBL12426952 0.87 HSP90AA1 (0.54) HSP90AA1ALDH1A1TDP1MAPK1MAPT
SCHEMBL11397350 0.87 HSP90AA1 (0.54) HSP90AA1ALDH1A1TDP1RECQLMAPT
SCHEMBL19243283 0.84 SMN1; SMN2 (0.53) HSP90AA1ALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL21017537 0.82 HSP90AA1 (0.50) HSP90AA1ALDH1A1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119868385-A Application of pyrroloquinoline-polyamine analogue combined with doxorubicin in preparation of antitumor drugs 河南大学 2025-04-25 CN claimed
CN-111163866-B Enhancement of acetylene hydrogenation catalysts using phosphorus ylide 切弗朗菲利浦化学公司 2023-05-09 CN claimed
EP-3681634-A1 USE OF PHOSPHOROUS YLIDES TO ENHANCE ACETYLENE HYDROGENATION CATALYSTS Chevron Phillips Chemical Company LP (US) 2020-07-22 EP claimed
CN-111163866-A Use of phosphorus ylide to enhance acetylene hydrogenation catalysts 切弗朗菲利浦化学公司 2020-05-15 CN claimed
US-10245583-B1 Use of charge-containing molecules linked with covalent bonds to enhance acetylene hydrogenation catalysts CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2019-04-02 US claimed
WO-2019055451-A1 USE OF PHOSPHOROUS YLIDES TO ENHANCE ACETYLENE HYDROGENATION CATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-03-21 WO claimed
US-20190076832-A1 USE OF CHARGE-CONTAINING MOLECULES LINKED WITH COVALENT BONDS TO ENHANCE ACETYLENE HYDROGENATION CATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2019-03-14 US claimed
CN-101395237-B Improvements in and relating to powder coating compositions crosslinked with non-cyanurate polyepoxides HEXION SPECIALTY CHEMICALS RES 2012-04-04 CN claimed
CN-101395237-A Improvements in and relating to powder coating compositions crosslinked with non-cyanurate polyepoxides HEXION SPECIALTY CHEMICALS RES (US) 2009-03-25 CN claimed
EP-0918810-B1 LOW TEMPERATURE CURE CARBOXYL TERMINATED POLYESTERS RESOLUTION SPECIALTY MATERIALS (US) 2005-03-09 EP claimed
US-6730812-B2 BALL-MILLING AND SALT FORMATION, CATALYTIC REACTION IN ONE POT; CATALYST SELECTIVITY, EFFICIENCY, LOW TEMPERATURE, SIMPLIFICATION; FORMING UNSATURATED COMPOUNDS, 4-BROMOSTYRENE, ISOPROPENYLNAPHTHALENE/1-/ IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2004-05-04 US claimed
US-20030176740-A1 Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-09-18 US claimed
WO-2003066548-A2 SOLVENT-FREE MECHANOCHEMICAL PREPARATION OF PHOSPHONIUM SALTS, PHOSPHORUS YLIDES, AND OLEFINS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2003-08-14 WO claimed
US-5492983-A COORDINATION CATALYST ECP ENICHEM POLYMERES FRANCE (FR) 1996-02-20 US claimed
US-12351686-B2 Curable resin composition, dry film and cured product of same, and electronic component containing said cured product TAIYO HOLDINGS CO., LTD. (JP) 2025-07-08 US disclosed
CN-119868385-A Application of pyrroloquinoline-polyamine analogue combined with doxorubicin in preparation of antitumor drugs 河南大学 2025-04-25 CN disclosed
CN-114269857-B Curable resin composition, dry film and cured product thereof, and electronic component comprising the cured product 太阳控股株式会社 2025-02-25 CN disclosed
US-4243683-A INSECTICIDES, MITICIDES MAY & BAKER LIMITED (GB) 1981-01-06 US disclosed
US-4183870-A Cyclopentane derivatives MAY & BAKER LIMITED (GB) 1980-01-15 US disclosed
US-4065620-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190076832-A1 USE OF CHARGE-CONTAINING MOLECULES LINKED WITH COVALENT BONDS TO ENHANCE ACETYLENE HYDROGENATION CATALYSTS YWHAZ, SLC6A12, CHRNE HSP90AA1 3289/4885ALDH1A1 2769/4885TDP1 3567/4885
US-20030176740-A1 Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins CCR4, CCR1, CCR6 HSP90AA1 4335/4885ALDH1A1 4791/4885TDP1 3762/4885
US-10245583-B1 Use of charge-containing molecules linked with covalent bonds to enhance acetylene hydrogenation catalysts YWHAZ, SLC6A12, CHRNE HSP90AA1 3289/4885ALDH1A1 2769/4885TDP1 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.