Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 9/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975660 | 0.80 | KDM4E (0.46) | MEN1KMT2ANOTUMHPGDALOX5AP | |
| SCHEMBL12920627 | 0.79 | ALOX5AP (0.57) | MEN1KMT2AALOX5AP | |
| SCHEMBL979095 | 0.79 | ALOX5AP (0.57) | MEN1KMT2AALOX5AP | |
| SCHEMBL977680 | 0.79 | MAPK14 (0.47) | HPGDALOX5APPDE10AKDM4EALDH1A1 | |
| SCHEMBL3000311 | 0.78 | ALOX5AP (0.52) | MEN1KMT2ANOTUMCXCR3HPGD | |
| SCHEMBL3713837 | 0.76 | HPGD (0.41) | HPGDALOX5APGPR119BRD4CREBBP | |
| SCHEMBL975773 | 0.75 | CYP1A2 (0.47) | HPGDALOX5APPDE10AKDM4EALDH1A1 | |
| SCHEMBL976155 | 0.75 | MAPK14 (0.47) | HPGDALOX5APPDE10AKDM4EALDH1A1 | |
| SCHEMBL977196 | 0.75 | CYP3A4 (0.44) | HPGDALOX5APPDE10AKDM4EALDH1A1 | |
| SCHEMBL976551 | 0.75 | PARP10 (0.56) | HPGDALOX5APKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | PTGIS, PTGS1, LTC4S | MEN1 4828/4885KMT2A 4659/4885NOTUM 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.