Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874547 | 0.71 | GPR3 (0.50) | GPR3MAPTTDP1POLBMEN1 | |
| SCHEMBL10371364 | 0.68 | AKR1B1 (0.43) | MAPTTDP1KMT2AKDM4EALDH1A1 | |
| Dibenzothiophene SCHEMBL17838083 | 0.68 | GPR3 (0.82) | GPR3MAPTTDP1POLBMEN1 | |
| Dibenzothiophene SCHEMBL28316922 | 0.67 | GPR3 (0.93) | GPR3MAPTTDP1POLBMEN1 | |
| SCHEMBL9534468 | 0.67 | CDK5 (0.51) | GPR3MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28268803 | 0.66 | KDM4E (0.68) | GPR3MAPTTDP1POLBMEN1 | |
| SCHEMBL4696033 | 0.66 | GPR3 (0.68) | GPR3MAPTTDP1POLBMEN1 | |
| SCHEMBL30515127 | 0.66 | GPR3 (0.68) | GPR3MAPTTDP1POLBMEN1 | |
| SCHEMBL29374932 | 0.66 | GPR3 (0.68) | GPR3MAPTTDP1POLBMEN1 | |
| SCHEMBL36332 | 0.66 | GPR3 (0.68) | GPR3MAPTTDP1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983603-A | ALZHEIMER*S DISEASE | SOCIETE ANONYME: SANOFI (FR) | 1991-01-08 | — | — | US | disclosed |