Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780344 | 0.85 | CA1 (0.50) | KIF11POLBEPHX2HTTMAPT | |
| SCHEMBL9780309 | 0.83 | KIF11 (0.50) | KIF11POLBEPHX2HTTMAPT | |
| SCHEMBL9780220 | 0.80 | POLB (0.50) | KIF11POLBEPHX2HTTMAPT | |
| SCHEMBL4410568 | 0.79 | GAA (0.66) | MAPTKMT2AMEN1RAB9ACA12 | |
| Hydrochloric Acid SCHEMBL9735996 | 0.78 | GAA (0.63) | MAPTKMT2AMEN1RAB9ACA12 | |
| SCHEMBL9734702 | 0.77 | CA1 (0.50) | KIF11POLBEPHX2MAPTKMT2A | |
| SCHEMBL23848234 | 0.77 | KIF11 (0.50) | KIF11POLBEPHX2HTTMAPT | |
| SCHEMBL10341659 | 0.77 | GLA (0.46) | POLBMAPTKMT2AMEN1CA12 | |
| SCHEMBL1948706 | 0.75 | MAPT (0.51) | KIF11POLBEPHX2HTTMAPT | |
| SCHEMBL13813682 | 0.75 | MAPT (0.51) | KIF11POLBEPHX2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4980356-A | ANTICONVULSANTS; ANTISPASMODIC AGENTS; MUSCULAR AND NERVOUS SYSTEMS DISORDERS | RHONE-POULENC SANTE (FR) | 1990-12-25 | — | — | US | disclosed |