Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | KIF11 | P52732 | 5/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341647 | 0.79 | RPS6KA2 (0.43) | CA1CA2CA12CA7MEN1 | |
| SCHEMBL9780212 | 0.77 | KIF11 (0.50) | CA1CA2KIF11EPHX2CA12 | |
| SCHEMBL10341662 | 0.77 | CA1 (0.44) | CA1CA2CA12CA7MEN1 | |
| SCHEMBL9736374 | 0.77 | MAPT (0.61) | CA1CA2CA12MEN1KMT2A | |
| SCHEMBL4418270 | 0.77 | CA1 (0.44) | CA1CA2KIF11FFAR1CA12 | |
| Hydrochloric Acid SCHEMBL9736836 | 0.77 | RPS6KA2 (0.42) | CA1CA2CA12CA7MEN1 | |
| SCHEMBL4411321 | 0.76 | ALDH1A1 (0.54) | CA1CA2CA12MEN1KMT2A | |
| SCHEMBL18361651 | 0.75 | CA2 (0.67) | CA1CA2KIF11CA12CA7 | |
| Hydrochloric Acid SCHEMBL10341636 | 0.75 | ALDH1A1 (0.52) | CA1CA2CA12MEN1KMT2A | |
| SCHEMBL10341650 | 0.74 | KDR (0.53) | CA1CA2CA7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358438-A2 | Ethanesulfonamide derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1990-03-14 | — | — | EP | claimed |
| US-5112866-A | Sulfonylfluorides as intermediates, also useful in treatment of bone disorders, antisecretory, antiulcer | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0358438-A2 | Ethanesulfonamide derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1990-03-14 | — | — | EP | disclosed |