Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.71 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377473 | 1.00 | DGKA (0.71) | DGKADNM1MAPTPAMADRA2A | |
| SCHEMBL1049974 | 1.00 | DGKA (0.71) | DGKADNM1MAPTPAMADRA2A | |
| SCHEMBL1056065 | 1.00 | DGKA (0.71) | DGKADNM1MAPTPAMADRA2A | |
| SCHEMBL7113175 | 1.00 | DGKA (0.71) | DGKADNM1MAPTPAMADRA2A | |
| SCHEMBL7114491 | 1.00 | DGKA (0.71) | DGKADNM1MAPTPAMADRA2A | |
| SCHEMBL7113105 | 1.00 | DGKA (0.71) | DGKADNM1MAPTPAMADRA2A | |
| Hydrochloric Acid SCHEMBL125089 | 0.98 | DGKA (0.69) | DGKADNM1MAPTPAMADRA2A | |
| Hydrochloric Acid SCHEMBL243866 | 0.98 | DGKA (0.69) | DGKADNM1MAPTPAMADRA2A | |
| Hydrochloric Acid SCHEMBL5907091 | 0.98 | DGKA (0.69) | DGKADNM1MAPTPAMADRA2A | |
| Bromide SCHEMBL10492800 | 0.95 | DGKA (0.65) | DGKADNM1MAPTPAMADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345650-B2 | Composition and method for the smoothing of fibres containing keratin | HENKEL AG & CO. KGAA (DE) | 2016-05-24 | — | — | US | disclosed |
| EP-1786520-B1 | COMPOSITION AND METHOD FOR THE SMOOTHING OF FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2016-03-09 | — | — | EP | disclosed |
| US-8900561-B2 | Hair treatment agents containing 4-morpholino-methyl-substituted silicone(s) and conditioning agent(s) | HENKEL AG & CO. KGAA (DE) | 2014-12-02 | — | — | US | disclosed |
| EP-2785321-A2 | HAIR TREATMENT AGENTS CONTAINING 4-MORPHOLINO-METHYL-SUBSTITUTED SILICONE(S) AND CONDITIONING AGENT(S) | Henkel AG & Co. KGaA (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-20140271750-A1 | HAIR TREATMENT AGENTS CONTAINING 4-MORPHOLINO-METHYL-SUBSTITUTED SILICONE(S) AND CONDITIONING AGENT(S) | HENKEL AG & CO. KGAA (DE) | 2014-09-18 | — | — | US | disclosed |
| EP-2056780-B1 | REDUCTIVE COLOUR REMOVAL | HENKEL AG & CO KGAA (DE) | 2013-08-14 | — | — | EP | disclosed |
| WO-2013079298-A2 | HAIR TREATMENT AGENTS CONTAINING 4-MORPHOLINO-METHYL-SUBSTITUTED SILICONE(S) AND CONDITIONING AGENT(S) | HENKEL AG & CO. KGAA (DE) | 2013-06-06 | — | — | WO | disclosed |
| EP-2594249-A2 | Hair treatment agent with cationic care agent and cationic tenside(s) | Henkel AG & Co. KGaA (DE) | 2013-05-22 | — | — | EP | disclosed |
| US-20110162670-A1 | Composition and Method for the Smoothing of Fibres Containing Keratin | HENKEL AG & CO. KGAA (DE) | 2011-07-07 | — | — | US | disclosed |
| EP-2277597-A1 | Reductive colour removal | Henkel AG & Co. KGaA (DE) | 2011-01-26 | — | — | EP | disclosed |
| EP-2056780-A1 | REDUCTIVE COLOUR REMOVAL | Henkel AG & Co. KGaA (DE) | 2009-05-13 | — | — | EP | disclosed |
| EP-2001559-A2 | REDUCTIVE COLOUR REMOVAL | Henkel AG & Co. KGaA (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2008055756-A1 | REDUCTIVE COLOUR REMOVAL | HENKEL AG & CO. KGAA (DE) | 2008-05-15 | — | — | WO | disclosed |
| US-20070267035-A1 | Composition and Method for the Smoothing of Fibres Containing Keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-22 | — | — | US | disclosed |
| WO-2007107313-A2 | REDUCTIVE COLOUR REMOVAL | HENKEL AG & CO. KGAA (DE) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267035-A1 | Composition and Method for the Smoothing of Fibres Containing Keratin | KRT18, HDAC10, PUF60 | DGKA 2499/4885DNM1 1657/4885MAPT 1126/4885 |
| US-20140271750-A1 | HAIR TREATMENT AGENTS CONTAINING 4-MORPHOLINO-METHYL-SUBSTITUTED SILICONE(S) AND CONDITIONING AGENT(S) | BHMT2, MGMT, SMC3 | DGKA 3406/4885DNM1 2948/4885MAPT 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.