Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR known ✓ | P25105 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869897 | 0.89 | SLC25A20 (0.46) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10870137 | 0.89 | SLC25A20 (0.46) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10871411 | 0.89 | SLC25A20 (0.46) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10870542 | 0.89 | SLC25A20 (0.46) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10870765 | 0.88 | BBOX1 (0.46) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10870772 | 0.88 | BBOX1 (0.46) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10869790 | 0.88 | BBOX1 (0.46) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10870932 | 0.86 | SLC25A20 (0.45) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10871031 | 0.86 | SLC25A20 (0.45) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10871233 | 0.86 | SLC25A20 (0.45) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047577-A | Activator For Peroxygen Laundry Bleach | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | claimed |