Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138445 | 0.84 | MAPT (0.51) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11252528 | 0.81 | GAA (0.70) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6020757 | 0.79 | LMNA (0.64) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6838994 | 0.79 | GAA (1.00) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13813682 | 0.77 | MAPT (0.51) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2095008 | 0.77 | MAPT (0.51) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6289309 | 0.77 | MAPT (0.55) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1948706 | 0.77 | MAPT (0.51) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6233494 | 0.77 | POLB (0.58) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6021145 | 0.76 | PDE4A (0.53) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4980356-A | ANTICONVULSANTS; ANTISPASMODIC AGENTS; MUSCULAR AND NERVOUS SYSTEMS DISORDERS | RHONE-POULENC SANTE (FR) | 1990-12-25 | — | — | US | disclosed |