Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780336 | 0.84 | GAA (0.65) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11090487 | 0.84 | GAA (0.46) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL4233355 | 0.82 | POLB (0.51) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL734644 | 0.80 | ICMT (0.44) | MAPTALDH1A1ALOX15TSHRRAB9A | |
| SCHEMBL747450 | 0.79 | POLB (0.59) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6233494 | 0.78 | POLB (0.58) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL13185886 | 0.77 | GAA (0.70) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12932849 | 0.76 | POLB (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12651873 | 0.76 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL20334822 | 0.76 | GAA (0.49) | MAPTALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143454-A1 | Pyrazoline Derivatives and Their Use As Pesticides | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090143454-A1 | Pyrazoline Derivatives and Their Use As Pesticides | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | US | disclosed |
| US-7345080-B2 | Substituted 4-pyrazolyl pyrazonlines used for pest control | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345080-B2 | Substituted 4-pyrazolyl pyrazonlines used for pest control | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345009-B2 | Reacting 4-phenyl pyraoline compound with phenyl isocyanate compound | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | MAURER FRITZ | 2008-03-13 | — | — | US | disclosed |
| EP-1569909-B1 | SUBSTITUTED PYRAZOLINE CARBOXANILIDES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2006-07-05 | — | — | EP | disclosed |
| US-20060128718-A1 | Tetrahydropyridazine derivatives having a pesticidal effect | BAYER CROPSCIENCE AG (DE) | 2006-06-15 | — | — | US | disclosed |
| US-20060100260-A1 | Substituted pyrazoline carboxanilides for use as pesticides | BAYER CROSCIENCE AG (DE) | 2006-05-11 | — | — | US | disclosed |
| EP-1569909-A1 | SUBSTITUTED PYRAZOLINE CARBOXANILIDES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| US-20050159603-A1 | Substituted 4-pyrazolyl pyrazonlines used for pest control | BAYER CROPSCIENCE AG (DE) | 2005-07-21 | — | — | US | disclosed |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-06-02 | — | — | US | disclosed |
| EP-1478644-A1 | SUBSTITUTED 4-PYRAZOLYL PYRAZOLINES USED FOR PEST CONTROL | Bayer CropScience AG (DE) | 2004-11-24 | — | — | EP | disclosed |
| EP-1474418-A1 | SUBSTITUTED 4-HETARYL-PYRAZOLINES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004052865-A1 | SUBSTITUTED PYRAZOLINE CARBOXANILIDES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-24 | — | — | WO | disclosed |
| EP-1412334-A1 | PYRAZOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003070724-A1 | SUBSTITUTED 4-PYRAZOLYL PYRAZOLINES USED FOR PEST CONTROL | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003066625-A1 | SUBSTITUTED 4-HETARYL-PYRAZOLINES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003010148-A1 | PYRAZOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | CYP4F3, CYP4X1, CYP4B1 | MAPT 4736/4885ALDH1A1 1185/4885MEN1 2222/4885 |
| US-20050159603-A1 | Substituted 4-pyrazolyl pyrazonlines used for pest control | L3MBTL4, L3MBTL3, PTMS | MAPT 4147/4885ALDH1A1 2215/4885MEN1 3003/4885 |
| US-20090143454-A1 | Pyrazoline Derivatives and Their Use As Pesticides | DDT, CHRM1, CHRM2 | MAPT 4108/4885ALDH1A1 990/4885MEN1 2148/4885 |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | CYP4X1, CYP4F3, DDT | MAPT 4785/4885ALDH1A1 1606/4885MEN1 3038/4885 |
| US-20060100260-A1 | Substituted pyrazoline carboxanilides for use as pesticides | DDT, CHRM2, CHRM1 | MAPT 4266/4885ALDH1A1 1840/4885MEN1 2209/4885 |
| US-20060128718-A1 | Tetrahydropyridazine derivatives having a pesticidal effect | DDT, ACHE, RDX | MAPT 3196/4885ALDH1A1 1579/4885MEN1 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.