SCHEMBL9780447

SCHEMBL9780447

CC(=O)Oc1cc(C(=O)Cl)cc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.49
ALDH1A1 P00352 7/20 0.45
MAPT P10636 6/20 0.45
HPGD P15428 3/20 0.45
SLC22A6 Q4U2R8 1/20 0.43
TSHR P16473 4/20 0.43
KDM4E B2RXH2 6/20 0.42
GAA P10253 4/20 0.42
RAB9A P51151 1/20 0.42
TOP1 P11387 5/20 0.42
POLB P06746 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
PTGS1 P23219 2/20 0.40
MAPK1 P28482 2/20 0.40
BLM P54132 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4961779 0.86 ALDH1A1 (0.56) HTTALDH1A1MAPTHPGDSLC22A6
Hydrochloric Acid SCHEMBL9780454 0.84 ALDH1A1 (0.54) HTTALDH1A1MAPTHPGDSLC22A6
SCHEMBL15012676 0.83 HTT (0.48) HTTALDH1A1MAPTHPGDSLC22A6
SCHEMBL3328123 0.80 HTT (0.48) HTTALDH1A1MAPTTSHRKDM4E
SCHEMBL27656394 0.79 HTT (0.53) HTTALDH1A1MAPTHPGDSLC22A6
SCHEMBL9035473 0.79 HTT (0.57) HTTALDH1A1MAPTHPGDSLC22A6
SCHEMBL6693971 0.79 HTT (0.53) HTTALDH1A1MAPTHPGDSLC22A6
SCHEMBL24955836 0.78 HTT (0.60) HTTALDH1A1MAPTHPGDSLC22A6
SCHEMBL9108459 0.78 ALDH1A1 (0.41) ALDH1A1MAPTHPGDTSHRKDM4E
SCHEMBL22435455 0.78 HTT (0.51) HTTALDH1A1MAPTHPGDSLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3044352-A None JP disclosed
JP-H0344352-A ESTER DERIVATIVE MITSUBISHI KASEI CORP 1991-02-26 JP disclosed