Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.62 |
| ▸ | TK2 | O00142 | 1/20 | 0.62 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780588 | 1.00 | TK1 (0.62) | TK1TK2RNASE1LMNASMN1; SMN2 | |
| SCHEMBL3388279 | 0.91 | TK1 (0.62) | TK1TK2RNASE1LMNASMN1; SMN2 | |
| SCHEMBL3388282 | 0.91 | TK1 (0.62) | TK1TK2RNASE1LMNASMN1; SMN2 | |
| SCHEMBL3388209 | 0.91 | TK1 (0.62) | TK1TK2RNASE1LMNASMN1; SMN2 | |
| SCHEMBL16360133 | 0.88 | RNASE1 (0.68) | TK1RNASE1LMNAALBPKM | |
| SCHEMBL6248265 | 0.88 | RNASE1 (0.68) | TK1RNASE1LMNAALBPKM | |
| SCHEMBL26571124 | 0.88 | RNASE1 (0.68) | TK1RNASE1LMNAALBPKM | |
| SCHEMBL9780793 | 0.88 | TK1 (0.51) | TK1TK2 | |
| SCHEMBL9780787 | 0.88 | TK1 (0.51) | TK1TK2 | |
| SCHEMBL10594576 | 0.88 | RNASE1 (0.59) | TK1TK2RNASE1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |