Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 8/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.60 |
| ▸ | TK2 | O00142 | 1/20 | 0.55 |
| ▸ | TK1 | P04183 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 2/20 | 0.54 |
| ▸ | PNP | P00491 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982022 | 1.00 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL5982018 | 1.00 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL2284783 | 1.00 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL231960 | 0.92 | DNMT1 (0.64) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL29431942 | 0.92 | DNMT1 (0.64) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL22299584 | 0.92 | DNMT1 (0.64) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL25837386 | 0.92 | DNMT1 (0.64) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL231959 | 0.92 | DNMT1 (0.64) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL1665903 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BTK2TK1 | |
| SCHEMBL1665907 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BTK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0258412-A1 | COMPOSITION FOR AND METHOD OF TREATING AIDS AND CERTAIN RELATED DISEASES | GREER, Sheldon B. (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004929-A1 | COMPOSITION FOR AND METHOD OF TREATING AIDS AND CERTAIN RELATED DISEASES | GREER SHELDON B | 1987-08-27 | — | — | WO | disclosed |
| US-4210638-A | 5-TRIFLUOROMETHYL-2'-DEOXYCYCTIDINE AND TETRAHYDROURIDINE OR 2'-DEOXYTETRAHYDROURIDINE | PCR, INC. (US) | 1980-07-01 | — | — | US | disclosed |