Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804389 | 0.79 | MEN1 (0.45) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL20553924 | 0.79 | MEN1 (0.45) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL27699889 | 0.79 | MEN1 (0.45) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL29290752 | 0.79 | MEN1 (0.45) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL28080162 | 0.79 | MEN1 (0.45) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL27721837 | 0.79 | MEN1 (0.45) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL9781007 | 0.79 | PARP10 (0.37) | MAPK1SLC6A3ALDH1A1POLBKDM4E | |
| SCHEMBL27886029 | 0.78 | MEN1 (0.44) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL20981385 | 0.78 | MEN1 (0.43) | MEN1KMT2AAPAF1RGS12HSP90AA1 | |
| SCHEMBL9780893 | 0.76 | SCN9A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |