Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780998 | 0.83 | SCN9A (0.44) | SCN9ALCK | |
| SCHEMBL29027761 | 0.80 | CYP4F2 (0.37) | CHEK2LCKJAK2JAK1TYK2 | |
| SCHEMBL9780923 | 0.76 | CSNK1E (0.40) | — | |
| SCHEMBL9780896 | 0.76 | FAAH (0.34) | FOLH1LCK | |
| SCHEMBL28388301 | 0.73 | HRH4 (0.46) | LCK | |
| SCHEMBL27467963 | 0.73 | HTR1A (0.40) | LCK | |
| SCHEMBL28381769 | 0.73 | HRH4 (0.39) | — | |
| SCHEMBL9781007 | 0.73 | PARP10 (0.37) | LCK | |
| SCHEMBL10918140 | 0.72 | PKM (0.43) | LCK | |
| SCHEMBL9781024 | 0.72 | HTR1A (0.37) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |