Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388301 | 0.85 | HRH4 (0.46) | PARP10HRH4POLBL3MBTL1SLC6A2 | |
| SCHEMBL28381769 | 0.81 | HRH4 (0.39) | PARP10HRH4POLBL3MBTL1SLC6A2 | |
| SCHEMBL9780998 | 0.79 | SCN9A (0.44) | SLC6A2SLC6A4SLC6A3PARP1MAPK1 | |
| SCHEMBL9780923 | 0.79 | CSNK1E (0.40) | POLBSLC6A3MAPK1HSD17B10KDM4E | |
| SCHEMBL5006032 | 0.78 | MAPK1 (0.45) | PARP10SLC6A2SLC6A4SLC6A3PARP1 | |
| SCHEMBL8581956 | 0.76 | PLA2G10 (0.42) | PARP10POLBL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL17474254 | 0.76 | HTR1A (0.42) | PARP10POLBL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL28384582 | 0.76 | PARP1 (0.38) | PARP10SLC6A2SLC6A4SLC6A3PARP1 | |
| SCHEMBL28004768 | 0.75 | HTR1A (0.35) | HRH4SLC6A2SLC6A4SLC6A3PARP1 | |
| SCHEMBL10918140 | 0.74 | PKM (0.43) | PARP10SLC6A2SLC6A4SLC6A3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |