Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.45 |
| ▸ | TK2 | O00142 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780930 | 1.00 | TK1 (0.45) | TK1TK2BCHE | |
| SCHEMBL10522602 | 0.91 | TK1 (0.56) | TK1TK2BCHE | |
| SCHEMBL10522597 | 0.91 | TK1 (0.56) | TK1TK2BCHE | |
| SCHEMBL9780986 | 0.87 | TK1 (0.53) | TK1TK2 | |
| SCHEMBL2035886 | 0.87 | TK1 (0.53) | TK1TK2 | |
| SCHEMBL13769962 | 0.86 | TK1 (0.53) | TK1BCHE | |
| SCHEMBL14217396 | 0.81 | TK1 (0.44) | TK1TK2BCHE | |
| SCHEMBL10449410 | 0.81 | TK1 (0.46) | TK1TK2 | |
| SCHEMBL14217401 | 0.80 | TK1 (0.40) | TK1TK2BCHE | |
| SCHEMBL13366936 | 0.79 | TK1 (0.50) | TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |
| US-4841039-A | 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents | EMORY UNIVERSITY (US) | 1989-06-20 | — | — | US | disclosed |
| US-4681933-A | 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1987-07-21 | — | — | US | disclosed |