Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1985376 | 0.86 | HPGD (0.40) | CYP3A4CYP2C19MEN1KMT2AALDH1A1 | |
| Water SCHEMBL4812408 | 0.73 | TP53 (0.40) | CYP3A4MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17321559 | 0.70 | ESR1 (0.37) | ALDH1A1ESR1 | |
| Hydrochloric Acid SCHEMBL28205666 | 0.69 | ALDH1A1 (0.41) | CYP3A4CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL9762821 | 0.67 | HPGD (0.48) | CYP3A4CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL27569486 | 0.67 | TP53 (0.48) | CYP3A4ALDH1A1TSHRHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL27744620 | 0.65 | TP53 (0.46) | CYP3A4MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3188266 | 0.65 | HPGD (0.44) | CYP3A4CYP2C19MEN1KMT2AALDH1A1 | |
| Water SCHEMBL27535675 | 0.65 | TP53 (0.46) | CYP3A4ALDH1A1TSHRHPGDKDM4E | |
| Iodide SCHEMBL27691445 | 0.65 | TP53 (0.46) | CYP3A4ALDH1A1TSHRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3261790-A | — | — | None | — | — | JP | disclosed |
| JP-H03261790-A | DIPHOSPHORANYLIDENEAMMONIUM SALT DERIVATIVE AND NONMEDICAL GERMICIDE | HOKKO CHEM IND CO LTD | 1991-11-21 | — | — | JP | disclosed |