Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177352 | 0.86 | HSD17B10 (0.63) | CFDLMNAGAABACE1HSD17B10 | |
| SCHEMBL154474 | 0.83 | LMNA (0.64) | LMNAGAAHSD17B10MAPTMEN1 | |
| SCHEMBL11579928 | 0.81 | LMNA (0.61) | LMNAGAAHSD17B10MAPTMEN1 | |
| SCHEMBL28599109 | 0.81 | LMNA (0.61) | LMNAGAAHSD17B10MAPTMEN1 | |
| SCHEMBL27935472 | 0.79 | BACE1 (0.70) | CFDLMNAGAABACE1HSD17B10 | |
| SCHEMBL14710190 | 0.79 | LMNA (0.46) | CFDLMNAGAABACE1HSD17B10 | |
| SCHEMBL3453107 | 0.79 | LMNA (0.50) | CFDLMNAGAABACE1HSD17B10 | |
| SCHEMBL13867886 | 0.78 | BACE1 (0.58) | CFDLMNABACE1HSD17B10MAPT | |
| SCHEMBL10237396 | 0.78 | LMNA (0.57) | LMNAGAAHSD17B10MAPTMEN1 | |
| SCHEMBL8477621 | 0.78 | HSD17B10 (0.63) | LMNAGAABACE1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3261745-A | — | — | None | — | — | JP | disclosed |
| JP-H03261745-A | AZULENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT USING THE SAME DERIVATIVE | MITSUBISHI KASEI CORP | 1991-11-21 | — | — | JP | disclosed |