SCHEMBL3453107

SCHEMBL3453107

CC(=O)Oc1cc(Br)cc(OC(C)=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
MAPT P10636 3/20 0.50
KDM4E B2RXH2 3/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 1/20 0.50
TTR P02766 1/20 0.50
TP53 P04637 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CYP19A1 P11511 1/20 0.46
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
BACE1 P56817 1/20 0.44
CFD P00746 2/20 0.42
POLB P06746 2/20 0.42
PKM P14618 1/20 0.42
ACHE P22303 2/20 0.41
ELANE P08246 2/20 0.41
HSD17B10 Q99714 1/20 0.39
GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14710190 0.95 LMNA (0.46) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL5534885 0.93 LMNA (0.45) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL10765006 0.92 KMT2A (0.44) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL27725727 0.87 CYP3A4 (0.53) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL2010436 0.87 LMNA (0.59) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL13141031 0.87 LMNA (0.53) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL4563723 0.86 LMNA (0.40) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL16952030 0.86 CTSL (0.41) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL903399 0.86 CYP4F2 (0.59) LMNAMAPTKDM4ECYP3A4MEN1
SCHEMBL16960965 0.86 LMNA (0.40) LMNAMAPTKDM4ECYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10000604-B2 Polymer and compensation film and optical film and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-06-19 US disclosed
US-20170183446-A1 POLYMER AND COMPENSATION FILM AND OPTICAL FILM AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-29 US disclosed
US-20170183446-A1 POLYMER AND COMPENSATION FILM AND OPTICAL FILM AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-29 US disclosed
CN-101117317-B Process for the preparation of stilbene derivatives DSM IP ASSETS BV 2011-10-12 CN disclosed
US-7820848-B2 Process for the preparation of stilbene derivatives DSM IP ASSETS B.V. (NL) 2010-10-26 US disclosed
CN-101117317-A Process for the preparation of stilbene derivatives DSM IP ASSETS BV (NL) 2008-02-06 CN disclosed
CN-100348564-C Process for preparing stilbene derivatives DSM IP ASSETS BV (NL) 2007-11-14 CN disclosed
US-20070197819-A1 Process for the preparation of stilbene derivatives DSM IP ASSETS B.V. (NL) 2007-08-23 US disclosed
CN-1845889-A Process for preparing stilbene derivatives DSM IP ASSETS BV (NL) 2006-10-11 CN disclosed
EP-1663926-A2 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES DSM IP Assets B.V. (NL) 2006-06-07 EP disclosed
WO-2005023740-A2 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES DSM IP ASSETS B.V. (NL) 2005-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197819-A1 Process for the preparation of stilbene derivatives VRK1, HPD, SIK1 LMNA 2910/4885MAPT 2686/4885KDM4E 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.